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TECH: Unfortunately, Marijuana Ineffective as Treatment for Alzheimers



Over the past year or so I have heard a lot of talk about how Marijuana is good for treating Alzheimers.  It made sense at the time, but unfortunately it seems that those were just stories.

 

The findings, published in the current issue of the journal Current Alzheimer Research, could lower expectations about the benefits of medical marijuana in combating various cognitive diseases and help redirect future research to more promising therapeutics.

Previous studies using animal models showed that HU210, a synthetic form of the compounds found in marijuana, reduced the toxicity of plaques and promoted the growth of new neurons. Those studies used rats carrying amyloid protein, the toxin that forms plaques in the brains of Alzheimer's victims.

The new study, led by Dr. Weihong Song, Canada Research Chair in Alzheimer's Disease and a professor of psychiatry in the UBC Faculty of Medicine, was the first to test those findings using mice carrying human genetic mutations that cause Alzheimer's disease -- widely considered to be a more accurate model for the disease in humans.

"As scientists, we begin every study hoping to be able to confirm beneficial effects of potential therapies, and we hoped to confirm this for the use of medical marijuana in treating Alzheimer's disease," says Song, a member of the Brain Research Centre at UBC and VCH Research Institute and Director of Townsend Family Laboratories at UBC.

"But we didn't see any benefit at all. Instead, our study pointed to some detrimental effects."

Source: www.sciencedaily.com

 

It looks like they injected mice with heavy doses of HU210, more commonly known as cannabinoid.  The doses were from 100 to 800 times that which most marijuana smokers get.  In the end there was no benefit, but some signs of greater plaque buildup.

What I want to know, where do I get my hands on cannabinoids?

Updated: 02/08/2010 17:59 Add to Favorite   Send Message   Send Story to a Friend   Bookmark and Share
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Article tags:    Alzheimers    Cannabinoids    HU210    Marijuana   
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